Its not really
a bike issue (I'm assuming your bike is a 4 stroke, 2-strokes can be temperamental), but as MM states, about you.
It is a long trek for a 125 (bear in mind on a CBT you won't be able to use motorways), but more than that, and especially if you're a relative newbie, it's quite a time to keep up your concentration; on a bike, any "little" error is potentially life-changing, if not life threatening (unlike a car where a minor lapse in concentration may be little more than a bent wing).
Bear in mind that with winter coming up, a long trek on a bike (even a big bike) can be hard work anyway.
Do also bear in mind that long rides in your locality is one thing - doing it on unfamiliar territory can be something else.
Do: check the weather forecast - I got caught out by snow going up to Scotland - in May! Some cold weather gear may be a good idea, as are heated grips if you haven't got them.
Carry spare fuel: running out is not fun. And fill up before you need to, so you don't panic about it. Also, carry some cash to pay for fuel; filling up and being told that the card payment system doesn't work is a headache you don't want.
Check your bike over mechanically: get any niggling faults sorted, fluid levels checked, tyres checked (pressures and damage), chain tension & lubrication, battery. Carry a few spares (bulbs & fuses, and perhaps spark plugs too), and some tools (even if its only the kit that came with the bike).
Keep a mobile: make sure its charged, and has enough credit on it. If possible, make sure you can get assistance from at least one person you know (family / friend / other half), particularly (without being sexist or degrading) as you're a lone female.
Plan your route, even if you're using sat-nav: sat-navs can get you "lost", or take you into some weird and / or undesirable areas. Try to do your run in daylight (that way, you can see the road surface better, and also less likely to come a cropper with suicidal rabbits or deer).
Make sure you've got sufficient space for everything your taking - leaving half your stuff at home because you can't get it on the bike will be at best inconvenient.
Get plenty rest the night before, and check you've organised everything: you don't want to forget something because your in a last-minute rush. Be aware of fatigue kicking in.
As obvious as it may sound, have you checked for secure parking for uni (both on campus, and your residence)?
Also, check Youtube for methods to pick up a dropped bike - it happens to the best of us occasionally; can be bloody unfunny if it happens when your single handed, and your bike loaded up.